Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and check in about potential interactions with other supplements or medications. It'll also cover the potential side effects, precautions, drug interactions, and dosage information for this herbal supplement. Asthma John D. Mark MD, in Integrative Medicine (Fourth Edition), 2018 Boswellia ( Boswellia serrata) Boswellia (also known as salai guggal or Indian frankincense) is a botanical used frequently in Ayurvedic medicine and traditionally used for inflammatory disorders, such as asthma and arthritis. Sontakke, S., Thawani, V., Pimpalkhute, S., Kabra, P., Babhulkar, S., and Hingorani, L. Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee. The tree is confined to Tropical Dry . After four weeks, those who took the Boswellia extract needed to use their inhalers about half as often as those who did not take the supplement. However, the result suggested Boswellia serrata was generally safe and well tolerated, even with long-term use. Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from, Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha. View abstract. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. View abstract. The tree is also known as Indian Frankincense or olibanum. It is an herbal remedy that is often used in Ayurveda, one of the oldest alternative health practices in the world. Boswellia sacra (also frankincense and olibanum-tree) is a tree in the Burseraceae family, which is the primary tree in the genus Boswellia from which is frankincense (a resinous dried sap) is harvested. This is Boswellia sacra, better known as the. If you buy through links on this page, we may earn a small commission Heres our process. Supplements besides Boswellia sometimes used to help manage IBD include: Regardless of your health conditions, you should always consult with a healthcare provider before starting a new supplement. By Brittany Lubeck, RD Browse 2,700+ boswellia tree stock photos and images available, or search for indian frankincense or frankincense plant to find more great stock photos and pictures. WebMD does not provide medical advice, diagnosis or treatment. Pure frankincense essential oil may also deliver active compounds to the body. The holiest plant of the Christmas season may be a raggedy shrub with peeling bark that seems to grow best in a dusty backyard in Tempe, Ariz. Mol.Pharmacol. Planta Med 2002;68(5):397-401. Thus, boswellic acid appears to block off the allergic response that causes an asthma reaction in the first place. Minerva Ginecol. View abstract. ex Colebr. View abstract. Eur J Med Res. Gregory PJ, Sperry M, Wilson AF. Boswellia serrata is a plant that produces Indian frankincense. Resin made from boswellia extract has been used for centuries in Asian and African. Use of this Web site does not create an expressed or implied physician-patient relationship. No events of Boswellia overdose or toxicity have been reported. B. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. This may be more likely when using topical Boswellia. Additional studies suggest benefits in patients with oral aphthous lesions(49), bronchial asthma(8), ulcerative colitis(9), mild irritable bowel syndrome(38)(50), and osteo-muscular pain(36). Boswellia Benefits Other Ingredients. Efficacy and safety of Aflapin, a novel Boswellia serrata extract, in the treatment of osteoarthritis of the knee: a short-term 30-day randomized, double-blind, placebo-controlled clinical study. In clinical studies, boswellia extracts(11)(44)(52)(53); a formulation containing boswellia, Terminalia chebula and turmeric(39); as well as boswellic acid combined with curcumin(40) were all reported useful in patients with osteoarthritis although data are conflicting(48). Inflammopharmacology 2022;30(2):477-486. Biol Pharm Bull. Inflamm Bowel Dis 2011;17:573-82. Carcinogenesis 2002;23:2087-93. Drug Metab Pers Ther. Pungle P, Banavalikar M, Suthar A, et al. It is also available in supplemental forms to support joint health. Language links are at the top of the page across from the title. Our highly-specialized educational programs shape leaders to be at the forefront of cancer care and research. This could change the effects and side effects of these medications. J Immunol 3-1-2006;176(5):3127-3140. 2020;35(2):/j/dmdi.2020.35.issue-2/dmpt-2020-0104/dmpt-2020-0104.xml. We include products we think are useful for our readers. However, this study used rats, so the results may not apply to humans. Managing ulcerative colitis in remission phase: usefulness of Casperome, an innovative lecithin-based delivery system of Boswellia serrata extract. Other Common Names: Indian frankincense, salai guggal (guggul), shallaki. Regardless, it's important to take Boswellia still as directed and avoid taking more than you should. One clinical study found the gum resin from the Boswellia serrata tree to be an effective treatment option for chronic colitis, a type of IBD. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Safety Considerations: Boswellia is likely safe, and side effects are typically minimal. You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. Br.J Pharmacol. Clark, C. E., Arnold, E., Lasserson, T. J., and Wu, T. Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis. Eur Rev Med Pharmacol Sci 2016;20(12):2695-700. Effects of gum resin of Boswellia serrata in patients with chronic colitis. View abstract. Chitre D, Nadkarni S, Jagtap N, et al. View abstract. However, the researchers wrote that additional higher-quality, large trials studying varying dosages are needed. Gupta I, Parihar A, Malhotra P, et al. View abstract. Boswellia's scientific name is Boswellia serrata. They recommend looking for capsules that contain 60% boswellic acid, as it is the active ingredient. Kirste S, Treier M, Wehrle SJ, et al. Double-blind trial of solid lipid Boswellia serrata particles (SLBSP) vs. standardized Boswellia serrata gum extract (BSE) for osteoarthritis of knee. Boswellia Serrata Tree (1 - 15 of 15 results) Price ($) Any price Under $25 $25 to $50 $50 to $100 Over $100 . Its growing financial center makes the city an increasingly important international business destination. View abstract. [2] Research Immunomodulatory activity of boswellic acids of Boswellia serrata Roxb. View abstract. Boswellia serrata is a resinous tree native to India, North Africa, and the Middle East. What Happens If I Take Too Much Boswellia? Boswellia, or Indian frankincense, is a resin herbal extract from the boswellia tree, which natural medicine practices have used for centuries. 2001;67(5):391-395. doi:10.1055/s-2001-15802. An association of boswellia, betaine and myo-inositol (Eumastos(R)) in the treatment of mammographic breast density: a randomized, double-blind study. Boswellia resin extract and propolis derived polyphenols in patients with type III chronic prostatitis/chronic pelvic pain syndrome: an Italian prospective multicenter study. Cochrane.Database.Syst.Rev. Hostanska, K., Daum, G., and Saller, R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Effect of a Boswellia and Ginger mixture on the memory dysfunction of the mild traumatic brain injury patients: a randomized, double-blind controlled trial. Coupling of boswellic acid-incuded Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes. View abstract. Some medications, such as those used after a transplant, decrease the activity of the immune system. View abstract. Mili N, Milosevi N, Golocorbin Kon S, Bozi T, Abenavoli L, Borrelli F. Warfarin interactions with medicinal herbs. doi:10.1007/978-3-319-41334-1_13, Ahmed M, Hwang JH, Choi S, Han D. Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review. 2008;36(6):1135-1142. It's important to store your supplements in a cool, dry place. Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Int J Med Sci 2010;7:366-77. 2016 Mar;29(1):140-6. 2019; 5(1) doi.org/10.1089/aivt.2018.0023. View abstract. Osteoarthritis Cartilage 2021;29(5):667-77. View abstract. Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage is appropriate for your individual needs. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M. I., Subramanian, L. R., and Ammon, H. P. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. Eur Rev Med Pharmacol Sci 2017;21(9):2249-54. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. J Chromatogr A 2006;1112:255-62. Dt rztebl 1997;94:1197. View abstract. The cream was applied twice daily during radiation therapy and was found to reduce both skin reddening and the need for topical steroids. Weber, C. C., Reising, K., Muller, W. E., Schubert-Zsilavecz, M., and Abdel-Tawab, M. Modulation of Pgp function by boswellic acids. For centuries, the versatile extract has been used in: Some studies suggest Boswellia may have anti-inflammatory effects and antioxidant effects. Minerva Gastroenterol Dietol 2019;65(1):30-5. The average dose of Boswellia is 300 milligrams (mg) three times a day. A 2016 review paper reports that boswellic acids might have antitumor properties and be toxic to cancerous cells. Allergic contact dermatitis from Boswellia carterii (frankincense) oil. Pellegrini L, Milano E, Franceschi F, et al. Boswellic acids inhibit glioma growth: a new treatment option? Boswellia serrata is a tree native to India, Africa, and the Arabian Peninsula. Boswellia resin has a rich scent and flavor. Unlike other non-steroidal anti-inflammatory drugs, however, it failed to show analgesic or antipyretic effects(16). Arzneimittelforschung 1998;48:668-74. 10-5-2003;795(2):355-362. Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Boswellia serrata is a tree prevalent in India, the Middle East and North Africa. 2007;82(1):91-93. Zegota Z, Gozdzik J, Glogowska-Szelag J. View abstract. It belongs to the Burseraceae family and is a deciduous tree that can grow 6-25ft depending on the species and location. 2015;19(19):37573762. "Oral herbal therapies for treating osteoarthritis", https://en.wikipedia.org/w/index.php?title=Boswellia_serrata&oldid=1126625161, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 10 December 2022, at 10:01. Wildfeuer A, Neu IS, Safayhi H, et al. Kiela PR, Midura AJ, Kuscuoglu N, et al. Bull Emerg Trauma. Phytochemistry 2003;62:537-41. Streffer JR, Bitzer M, Schabet M, et al. Safayhi, H., Sailer, E. R., and Ammon, H. P. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. This information may not fit your specific health circumstances. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin. iHerb is an online retailer of supplements and health and wellness products. View abstract. The U.S. Food and Drug Administration does not regulate dietary supplements in the same way as it does conventional food products and drugs. You can take boswellia in different ways, including taking it orally (by mouth) in a capsule, pill, or tablet, or using it as an oil that you can put on your body. 1995;47(6):1212-1216. Find help & information on Boswellia serrata incense tree from the RHS Boswellia supplements have also been studied for: It's also important to note that Boswellia supplements are not to be used in place of medical treatment for these and other uses. 2012;64(2):135-141. Boswellia is thought to suppress inflammation that is present in asthma, opening up a path for normal breathing. In animal models, boswellia had an anti-inflammatory and antioxidant effect, which appeared to protect neurons in the brain and improve motor function in a rat model of Parkinsons disease. 2008;(2):CD003575. It can also be found in soaps, lotions, detergents, and perfumes. Supplements have become more popular over the years, and typically, there is more than one that may benefit you. The resin is rich in triterpenic acids and has been used for centuries in traditional Ayurvedic medicine to treat inflammatory conditions. Mol Med Rep 2013;8(5):1542-8. Burseraceae) is a mastic tree, and the resin collected from its stem has been long used in Indian traditional medicine. Ferrara T, De Vincentiis G, Di Pierro F. Functional study on Boswellia phytosome as complementary intervention in asthmatic patients. 802. from $51/night. A mix of the charming, modern, and tried and true. doi:10.1002/14651858.CD002947.pub2. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. Phytother Res 2019;33(5):1457-68. Barueri. Roy, S., Khanna, S., Krishnaraju, A. V., Subbaraju, G. V., Yasmin, T., Bagchi, D., and Sen, C. K. Regulation of vascular responses to inflammation: inducible matrix metalloproteinase-3 expression in human microvascular endothelial cells is sensitive to antiinflammatory Boswellia. Farmers tap the tree to collect its resin, which is called boswellia. Semantic Scholar extracted view of "Manual de biossegurana" by M. H. Hirata et al. Safety and toxicological evaluation of a novel, standardized 3-O-acetyl-11-keto-beta-boswellic acid (AKBA)-enriched Boswellia serrata extract (5-Loxin). Contact Dermatitis 2004;51:91-2. Title 21. Scientific research is beginning to support the benefits of boswellia, but most studies to date have used cell or animal models.