All rights reserved. All rights reserved. Consult doctors online from the comfort of your home for free. Medicine used in the eyes is not likely to be affected by other drugs you use. Qualitative variables were correlated using Chi-square test/Fisher's exact test. Copyright: Merative US L.P. 1973, 2023. Similar results were reported in a study by Comez et al., in which the use of HPMC 0.3% and CMC 0.5% eye drops demonstrated significant improvement in TF-BUT as compared to the baseline, but there was no difference between the two groups. [Internet]. government site. Do not start, stop, or change the dosage of any medicines without your doctor's approval. The main limitations of the study are the inability to assess patient adherence to the therapy, use of an open-label study design, and the inability to include osmolarity testing. Future large-scale double-blind studies may be planned to validate the findings of the present study. 2019 Jul 20;566:111-125. doi: 10.1016/j.ijpharm.2019.05.059. Version: 1.01. cyclosporine ophthalmic, Restasis, varenicline, Xiidra, Systane, Artificial Tears. Your safety is our top priority. Injectable dosage form: Since this medicine is administered during eye surgeries, your surgeon will give you appropriate instructions. Breaking Barriers in Eye Treatment: Polymeric Nano-Based Drug-Delivery System for Anterior Segment Diseases and Glaucoma. Hydroxypropyl methylcellulose ophthalmic side effects, Detailed Hydroxypropyl methylcellulose ophthalmic dosage information, Drug class: ophthalmic lubricants and irrigations. The maximum score is 100, which indicates complete disability and a score of zero indicates no disability. Follow all directions on your prescription label and read all medication guides or instruction sheets. Comparison of Schirmer-I score between the two groups, *Values represent meanSD. Advertising revenue supports our not-for-profit mission. Particularly for ocular and ophthalmic formulations, HPMC is applied as viscosity enhancer agent in eye drops, gelling agent in injections, and polymeric matrix in films, filaments and inserts. Polymers (Basel). Group A participants, who received CMC 0.5% tear substitutes, showed a higher improvement in comparison with Group B who received HPMC 0.3%. In these cases, your doctor may want to change the dose, or other precautions may be necessary. [9], Only one study participant each from Group A and Group B had an initial burning sensation when they used the respective tear substitutes for the first time. [5], The Occupational Safety and Health Administration department of US Government has defined computer vision syndrome (CVS) as a complex of eye and vision problems that are experienced during and related to computer use; it is a repetitive strain disorder that appears to be growing rapidly in workers using computers for more than 3 h/day.[6], A key principle for the management of dry eye disease is an augmentation of tear film through the topical administration of artificial tear substitutes. These side effects may go away during treatment as your body adjusts to the medicine. Gender distribution of study participants. Preservatives are important in eye drops because they prevent bacterial growth and subsequent infection . If your dose is different, do not change it unless your doctor tells you to do so. Common side effects of Ofloxacin + Hydroxypropylmethylcellulose Eye irritation, Eye discomfort CONTENT DETAILS Written By Dr. Anuj Saini MMST, MBBS Reviewed By Dr. Ashish Ranjan MD (Pharmacology), MBBS Last updated 21 Apr 2020 | 09:16 AM (UTC) 0.1% dextran 70/0.3% hydroxypropyl methylcellulose 2910; . As compared to the baseline, there was an improvement in OSDI scores on all follow-up visits in both groups, and this difference was statistically significant. Many medicine have not been studied specifically in older people. Drug information provided by: Merative, Micromedex. Canada residents can call a provincial poison control center. If postoperative intraocular pressure increases above expected values, appropriate therapy should be administered. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. If you notice other effects not listed above, contact your doctor or pharmacist. Use the medicine exactly as directed. It works similar to natural tears and provides temporary relief from burning and discomfort due to dryness of the eye. sharing sensitive information, make sure youre on a federal It also lubricates and protects the eye. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Your doctor may direct you to also use an artificial tears solution or saline drops with this medication. Hydroxypropylmethylcellulose belongs to a class of medicines called eye lubricants or artificial tears. If you miss a dose, use it as soon as you remember. Inform the doctor if you have a known history of allergy to this medicine. Mayo Clinic does not endorse companies or products. The baseline OSDI score? [2] In the Indian population, hospital-based prevalence of dry eye has been reported to vary from 18% to 27%. Prevalence of and risk factors for dry eye syndrome. If any of these side effects bother you, please consult your doctor. Methylcellulose is a bulk-forming laxative that increases the amount of water in your stools to help make them softer and easier to pass. In addition, the participants were advised to report an ADR at any time. It is used to relieve dryness and irritation caused by reduced tear flow. Ask your doctor when you may replace your contact lenses. It has bioadhesive properties, and its anionic nature may be the reason for high retention time on the cornea. Data sources include IBM Watson Micromedex (updated 14 May 2023), Cerner Multum (updated 28 May 2023), ASHP (updated 10 Apr 2023) and others. This medicine may also cause your eyes to become more sensitive to light than they are normally. Blink several times after pouring the drops. The different therapeutic approaches are necessary due to the complex anatomic structure of the eye. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Nath PC, Debnath S, Sharma M, Sridhar K, Nayak PK, Inbaraj BS. This was a prospective, randomized, comparative, and open labeled study, conducted by enrolling the patients, visiting the outpatient clinic of department of ophthalmology. International Journal of Applied and Basic Medical Research, https://www.statista.com/statistics/272394/agedistribution-of-internet-users-in-india. Last updated on Sep 12, 2022. Some dosage forms listed on this page may not apply to the brand name Isopto Plain. [21] An earlier study shows that it may have a cytoprotective effect on the ocular surface when used before insertion of contact lens into the eye. The time taken for the first appearance of a dry spot was recorded as the tear film break up time or TF-BUT. For ophthalmic solution (eye drops) dosage form: Adults and childrenUse 1 drop three or four times a day. (a) Anatomy of eye. Drug class: ophthalmic lubricants and irrigations. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Serious side effects of Isopto Plain Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. It stabilizes the natural tear film and maintains necessary lubrication so your eyes dont get dry and irritated. Yusufu M, Liu X, Zheng T, Fan F, Xu J, Luo Y. Hydroxypropyl methylcellulose 2% for dry eye prevention during phacoemulsification in senile and diabetic patients. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. TF-BUT values increased for both the groups on subsequent follow-up visits, which is indicative of an improvement in dry eye symptoms [Table 4]. Do not use two doses at one time. Tell your doctor if you are pregnant or breastfeeding. It is used to soothe irritation, burning and discomfort of dry eye conditions. If you have any questions, ask your doctor or pharmacist. Store at room temperature away from heat. Before using hydroxypropyl cellulose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Keep out of the reach of children. 2023 Dec;30(1):2158964. doi: 10.1080/10717544.2022.2158964. This keeps the drug in your child's eye. You may report side effects to the FDA at 1-800-FDA-1088. If you are using it for dry eyes, instil 1 or 2 drops in the affected eye(s) as needed. In India, around 38% of internet users are in the age group of 2534 years. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. . Chen LC, Lin SY, Cheng WJ, Sheu MT, Chung CY, Hsu CH, Lin HL. Hydroxypropyl methylcellulose may also be used to moisten hard contact lenses and artificial eyes. The study procedures followed the Helsinki Declaration of 1975, as revised in 2000. Hypromellose ophthalmic is also used during certain eye surgeries to help maintain the shape of the eye, and to protect the tissues of the eye from injury. Preservatives are the component of artificial tears that may cause harm to the eye. Enjoy free home sample collection, view reports online and consult a doctor online for free. Store this medicine at room temperature. Other criteria for exclusion were a history of active ocular infection or ocular allergy, ocular surgery within 12 months, recurrent herpetic keratitis, use of contact lenses, systemic medications (such as diuretics, antidepressants, anxiolytics, and antihypertensives), and any systemic diseases/syndromes associated with dry eye (Sjogren's syndrome and other autoimmune diseases). FOIA Shake off any visible water droplets, and then replace the applicator in the storage container. Dry eyes Medicinal Benefits HYDROXYPROPYL METHYLCELLULOSE contains an eye lubricant, Hydroxypropyl methylcellulose. Keep from freezing. Many medicines have not been studied specifically in older people. Hypromellose ophthalmic (for the eyes) is used as an eye lubricant to treat dry irritated eyes. In addition, it may be used in certain eye examinations. Drug class: ophthalmic lubricants and irrigations. Remember not to use the eye drops after the expiry date or after 30 days of opening it. Three participants in one study had keratitis, hypersensitivity reactions, and conjunctival hyperemia,[17] while other studies have not reported any adverse effects with the use of CMC.[10,20]. Medically reviewed by Drugs.com on May 22, 2023. The normality of data was tested by KolmogorovSmirnov test. Chat privately with our registered medical specialists to connect directly with verified doctors. It is used to relieve dry eye conditions associated with the use of TVs and computers, atmospheric pollution, infrequent blinking, drying atmospheres, and certain medical treatments. Int J Pharm. Weve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Available for Android and iOS devices. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. You may experience visual disturbances and eye discharge while using this medicine. Your privacy is guaranteed. Hydroxypropyl methylcellulose ophthalmic 2% intraocular solution is for use as an ophthalmic surgical aid in anterior segment surgery. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Participants were advised to follow the 20-20-20 rule. As per this rule, participants were advised to look away from the computer at least every 20 min and gaze for at least 20 s at an object at least 20 feet away: this causes relaxation of the ocular muscles of accommodation. Adverse drug reaction (ADR) monitoring was done on all visits. Use the supplied applicator to place 1 insert into the eye, usually 1 to 2 times daily or as directed by your doctor. Gonak Hypromellose, Goniosol, Cellugel, Goniosoft, +3 more. Development and evaluation of performance characteristics of timolol-loaded composite ocular films as potential delivery platforms for treatment of glaucoma. Call your doctor for medical advice about side effects. This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. Along with its needed effects, a medicine may cause some unwanted effects. Mayo Clinic does not endorse companies or products. In addition to the tear substitute use, participants were advised to blink voluntarily more often during computer usage. Randomized, phase III study comparing osmoprotective carboxymethylcellulose with sodium hyaluronate in dry eye disease. We comply with the HONcode standard for trustworthy health information. Do not use while wearing soft contact lenses. sharing sensitive information, make sure youre on a federal This is not a complete list of possible side effects. You should consult your doctor about all the possible interactions of the drugs youre taking. eye redness or discomfort or other irritation not present before use of this medicine. [1] [2] Hydroxypropyl methylcellulose, the main ingredient of Hydroxypropyl Methylcellulose, is used in the form of eye drops as well as eye gels as an ocular lubricant for the treatment of dry eyes. Unable to load your collection due to an error, Unable to load your delegates due to an error. Do this for 1 to 2 minutes. If the eye system accidentally comes out of your eye, as sometimes occurs when the eye is rubbed, do not put it back in the eye, since it may be contaminated. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. This is the most frequently used survey instrument and is validated for the assessment of ocular surface disease severity in dry eye research. We comply with the HONcode standard for trustworthy health information. In this study, out of a total of 180 participants, 50.6% of participants were in the age group of 2130 years, while 30% of the participants were in the age group of 1820 years [Table 1]. GENTEAL EYE DROPS contains Hydroxypropyl Methylcellulose which belongs to the group of medicines called Demulcents. Methylcellulose may also be used for purposes not listed in this medication guide. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If you are allergic to hydroxypropyl methylcellulose; any part of hydroxypropyl methylcellulose; or any other drugs, foods, or substances. These products enhance tear stability and help to retain moisture in eye, thus relieving the symptoms of CVS. The amount of medicine that you take depends on the strength of the medicine. Hydroxypropyl methylcellulose (HPMC) is a cellulose ether widely used in drug formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior. Brand names: Cellugel, Gonak Hypromellose, Goniosoft, Goniotaire, Goniovisc, 8600 Rockville Pike Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Warnings Make sure your vision is clear before you drive, use machines, or do anything else that could be dangerous if you are not able to see well . WebMD does not provide medical advice, diagnosis or treatment. The Schirmer I-test values were comparable between the two groups on day 0 (12.86 mm for Group A and 13.12 mm for Group B; P = 0.341). It helps to soothe the irritation and burning seen in dry eyes by maintaining proper lubrication of the eyes. Close your eyes for 1 or 2 minutes. Bethesda, MD 20894, Web Policies This medicine is not recommended for use in patients with a known allergy to hydroxypropyl methylcellulose or any other inactive ingredients present along with it. Portions of this document last updated: Feb. 01, 2023. Ophthalmic lubricants and irrigations, Ophthalmic surgical agents, Consult top doctors online and get an answer now, Book an appointment with the top doctors near you, Copyright 2017, Practo. Drop the medicine into the pouch and gently close the eyes. The data was entered in MS EXCEL spreadsheet, and analysis was done using? Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Ursa-HPMC Eye Drop is an eye lubricant or artificial tears used to relieve dry eyes. Centaurpharma.com. Do not keep outdated medicine or medicine no longer needed. Do not touch the tip of the eye dropper or place it directly on your eye. >= 6 years: 1 to 2 drops as needed. The values of TF-BUT improved in both groups, the difference being statistically insignificant. Bookshelf official website and that any information you provide is encrypted During pregnancy, this medication should be used only when clearly needed. [3], The etiology of dry eye still remains unclear though some known risk factors are older age, female gender, arthritis, smoking, hormone-replacement therapy, and environmental factors such as low relative humidity. To help you remember, use it at the same time(s) each day. Before opening the package containing this medicine, wash your hands thoroughly with soap and water. Although there is no specific information comparing use of hydroxypropyl methylcellulose in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. Hypromellose ophthalmic may also be used for purposes not listed in this medication guide. Keep from freezing. National Library of Medicine Note: This document contains side effect information about hydroxypropyl methylcellulose ophthalmic. Take care not to float the lens from your eye when applying this medicine. cyclosporine ophthalmic, Restasis, varenicline, Xiidra, Systane, Artificial Tears. Participants of both genders aged 18 years and above with an average computer use of 3 h at a stretch per day or 15 h a week for at least 3 months presenting with ocular symptoms (blurring of vision, headache, dry eyes, redness of eyes, or eye strain) were considered to have CVS.[11]. Last updated on May 27, 2022. Hence, it could be concluded that CMC and HPMC provide a similar efficacy in CVS. Use those medications exactly as prescribed. Li P, Wang S, Chen H, Zhang S, Yu S, Li Y, Cui M, Pan W, Yang X. All rights reserved, Practo Technologies Pvt. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Eye; Hydroxypropyl methylcellulose; Ocular drug delivery; Ocular formulations. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. . Do not administer in larger or smaller amounts than advised/prescribed. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. All the risks and benefits should be discussed with the doctor before using/receiving this medicine. Talebian S, Mendes B, Conniot J, Farajikhah S, Dehghani F, Li Z, Bitoque D, Silva G, Naficy S, Conde J, Wallace GG. Many people using this medication do not have serious side effects. It helps prevent damage to the eye in certain eye diseases. Medically reviewed by Drugs.com. It was placed in the lower conjunctival sac at the junction of the outer one-third and medial two-thirds of the lower eyelid. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Notify your doctor if it persists for longer. Injection: This medicine should be administered by a qualified healthcare professional. Quantitative variables were compared using MannWhitney test (as the data sets were not normally distributed) between the two groups and Wilcoxon ranked sum test within the group across follow-up. Epub 2023 Feb 13. (b) Routes of administration: eye drops (D), films (F), lens (L) for topical administration; inserts (I), gel subconjuctival injection (SI) and intravitreal injection (II) for non-topical administration. Mhra.gov.uk. OSDI score, used as the primary efficacy parameter, was comparable in Group A and B at baseline: 23.38 and 23.32, respectively, with a P = 0.728. Do not use the medicine if it looks cloudy or has changed colors. Skip any missed dose if it's almost time for your next dose. Accessibility Albietz JM, Lenton LM, McLennan SG, Earl ML. This medication is an insert that is placed in your eye to treat dry eyes. Usual Adult Dose for Eye Dryness/Redness: Ophthalmic drops: 1 to 2 drops as needed. Garrett Q, Simmons PA, Xu S, Vihege J, Zhao Z, Ehrmann K, et al. Hypromellose ophthalmic is also used during certain eye surgeries to help maintain the shape of the eye, and to protect the tissues of the eye from injury during the procedure. Systane, Artificial Tears, Refresh, Systane Ultra, +79 more. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. This is a decision you and your doctor will make. This medicine may be harmful if swallowed. It is inserted in the eye to relieve dryness and irritation caused by reduced tear flow that occurs in certain eye diseases. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Hydroxypropyl methylcellulose ophthalmic 2% intraocular solution is for use as an ophthalmic surgical aid in anterior segment surgery. It works similar to natural tears and provides temporary relief from burning and discomfort due to dryness of the eye. This document does not contain all possible drug interactions. India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform. Follow all directions on your medicine label and package. It is also used in the form of injection as a surgical aid during certain eye surgeries. Available from: [Internet]. Description Hydroxypropyl methylcellulose, the main ingredient of Hydroxypropyl Methylcellulose, is used in the form of eye drops as well as eye gels as an ocular lubricant for the treatment of dry eyes. Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations. Sen A, Richardson S. A study of computer-related upper limb discomfort and computer vision syndrome. To overcome the lack of eye drops, an alternative type of ophthalmic in situ gel has been developed. The https:// ensures that you are connecting to the However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Schirmer test I (Schirmer test without anesthesia) measures basic plus reflex tear secretion. Poloxamer sols endowed with in-situ gelability and mucoadhesion by adding hypromellose and hyaluronan for prolonging corneal retention and drug delivery. 2018 [cited 31 December 2018]. Usual Pediatric Dose for Eye Dryness/Redness: Ophthalmic drops:>= 6 years: 1 to 2 drops as needed.The ophthalmic 2% intraocular solution is for use as an ophthalmic surgical aid in anterior segment surgery. Using alcohol or tobacco with certain medicines may also cause interactions to occur. SPSS (Statistical Package for the Social Sciences) software version 21.0 IBM, Chicago,USA. Hold the dropper above the eye and squeeze a drop into this pocket. 2023 Mar 9;15(6):1373. doi: 10.3390/polym15061373. Comparison of ocular surface disease index score between the two groups at follow-up visits. This is a decision you and your doctor will make. Accessibility All rights reserved. [14] About 51% of participants who were diagnosed with CVS in our study are in the age group of 2130 years. Adv Sci (Weinh). Dry Eye Disease Hydroxypropyl cellulose (Ophthalmic) Print Save Hydroxypropyl cellulose (Ophthalmic) Generic name: hydroxypropyl cellulose [ hye-drox-ee-PROE-pil-SEL-ue-lose ] Drug class: Ophthalmic lubricants and irrigations Medically reviewed by Drugs.com. Hypromellose ophthalmic is also used during certain eye surgeries to help maintain the shape of the eye, and to protect the tissues of the eye from injury during the procedure. Do not give hypromellose ophthalmic to a child without medical advice. Precaution. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Ltd., Salarpuria Symbiosis, Arekere Village, Begur Hobli, Bannerghatta Main Rd, Bengaluru, Karnataka 560076. This was a prospective, randomized, comparative, and open-labeled study. People are spending more time in front of the screen, and hence higher number of cases of CVS are likely to be seen in clinical practice. It is used to alleviate dry eye conditions by substituting tear fluid in affected individuals. Consult your doctor if you are not sure. Follow your doctor's orders or the directions on the label. Geriatric . ATPs are lubricant eye drops used to treat the dryness and irritation associated with DED. The different types of formulations (local application) including HPMC for ocular drug delivery are discussed with basis on recent literature reports and patents. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 2018 [cited 1 June 2018]. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. This medicine is available only with your doctor's prescription. A TF-BUT of <10 s was taken as dry eye. Vehige JG, Simmons PA, Anger C, Graham R, Tran L, Brady N. Cytoprotective properties of carboxymethyl cellulose (CMC) when used prior to wearing contact lenses treated with cationic disinfecting agents. Rinse the applicator with hot running water after use. Hydroxypropyl methylcellulose belongs to the group of medicines known as artificial tears. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Some other side effects of this medicine include redness of the eye, eye irritation, burning and discomfort, eyelid swelling and itching of the eye. The .gov means its official. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Learn all preparation and usage instructions. Methylcellulose is used to treat constipation and to help maintain regular bowel movements. In this study, we compared the efficacy and safety of two commonly used tear substitutes containing CMC 0.5% and HPMC 0.3% in participants diagnosed with dry eye due to CVS. Before ATPs are lubricant eye drops used to treat the dryness and irritation associated with DED. Effects of lubricating agents with different osmolalities on tear osmolarity and other tear function tests in patients with dry eye. The relationship between chemical structure and physicochemical properties of HPMC is displayed. Drug class: Ophthalmic lubricants and irrigations. We evaluated the efficacy and safety of two commonly used tear substitutes, CMC and HPMC in participants in the age group of 1860 years. Stinging sensation may occur for 1-2 minutes. The following information includes only the average doses of this medicine. As a library, NLM provides access to scientific literature. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. Do not share this medication with others. Schiffman R, Christianson M, Jacobsen G, Hirsch JD, Reis BL. Although not all of these side effects may occur, if they do occur they may need medical attention. Call your doctor for medical advice about side effects. The .gov means its official. Before . Comez AT, Tufan HA, Kocabiyik O, Gencer B. Disclaimer. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). What do I need to tell my doctor BEFORE I take Hydroxypropyl Methylcellulose? If you have any questions about this, check with your doctor. Clipboard, Search History, and several other advanced features are temporarily unavailable.